Vahedian-Azimi A, Bianconi V, Makvandi S, et al. What Happens if You Eat Grapefruit While on Statins A peculiar cross-reaction with a specific food exists with Lipitor and other 'statin' drugs used to lower. Other minor side effects include constipation, diarrhea, fatigue, gas, heartburn, and headache.
GRAPEFRUIT AND ATORVASTATIN INTERACTION TRIAL
HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment. Lipitor should be used with caution in patients with alcohol or other liver diseases.
Managing drug interactions in HIV-infected adults with comorbid illness. Recommendations for management of clinically significant drug-drug Interactions with statins and select agents used in patients with cardiovascular disease: A scientific statement from the American Heart Association. American Heart Association Clinical Pharmacology Committee of the Council on Clinical Cardiology Council on Hypertension Council on Quality of Care and Outcomes Research and Council on Functional Genomics and Translational Biology. Wiggins BS, Saseen JJ, Page RL 2nd, et al. In: Feingold KR, Anawalt B, Blackman MR, et al, eds. Clinical guidance for managing statin and antimicrobial drug-drug interactions. Hylton Gravatt LA, Flurie RW, Lajthia E, Dixon DL. Clinically relevant drug interactions between statins and antidepressants. Palleria C, Roberti R, Iannone LF, et al. National trends in statin use and expenditures in the US adult population from 2002 to 2013: Insights from the Medical Expenditure Panel Survey. Grapefruitdrug interactions that affect the pre-systemic metabolism (i.e., the metabolism that occurs before the drug enters the blood) of drugs have a different duration of action than interactions that work by other mechanisms, such as on absorption, discussed below. Salami JA, Warraich H, Valero-Elizondo J, et al. Centers for Disease Control and Prevention.
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